Atasasung kerta wara nugraha Ida Sang Hyang Widhi Wasa, perkenankanlah kami mengundang Bapak/Ibu/Saudara/i untuk berkenan hadir di acara Manusa Yadnya Pawiwahan & Mepandes (Potong Gigi) putra - putri kami yang akan dilaksanakan pada : JAKARTA dr. Bagus Putu Putra Suryana selaku SpPD-KR, Ketua Umum Perhimpunan Osteoporosis Indonesia (PEROSI) mengatakan Orang dengan usia lanjut atau lansia memiliki risiko berbagai ancaman penyakit tidak menular seperti jantung, stroke, dan lainnya termasuk osteoporosis. dr Putu Bagus Surya Witantra Giri, Sp.Ak, CHt is a Dokter Spesialis Akupuntur in Kota Jakarta Pusat. Book appointments online, view fees, user feedback for dr. Putu Bagus Surya Witantra Giri, Sp.Ak, CHt | Okadoc Dr I Gusti Bagus Rai Utama, MA . Dr. I Gusti Bagus Rai Utama, MA . Dr. I Gusti Bagus Rai Utama, MA . IDA BAGUS PUTU SANCITHA GUPTAYANA PUTRA FK Ilmu Keperawatan L 46 1002305008 PUTU AYU SITA SARASWATI Fisioterapi P 47 I NYOMAN SURYANA FT Mesin L 82 1008605029 ARDHI GUNAWAN SUARSA FMIPA Ilmu Komputer L 83 Jl WR Supratman No.14-19, Dangin Puri Kangin, Denpasar Utara. puriraharja@ 222013 (Rumah Sakit) (0361) 229118 (Poliklinik) IPUTU AGUS SUGIRI PUTRA, Politeknik Negeri Jakarta Pemilihan Mapres Tahun 2016 Final Pemilihan Mawapres tahun 2016 dilaksanakan di Jogyakarta pada tanggal 14-17 Agustus 2016, dibuka dan ditutup oleh oleh Direktur Kemahasiswaan Dr. Didin Wahidin. 30Dr. I Gede Setiawan Adi Putra, M.Si Denpasar 2614027 31 Ir. Dewa Nyoman Sadguna, M.Agb Denpasar 2614028 32 Ir. 61 Ir. Bagus Putu Udiyana, MP Denpasar 2614058 62 Ir. I Made Suryana, M.Si Denpasar 2614059 63 Ir. Ni Luh Pastini, M.Agb Denpasar 2614060 . 64 Ir. Cening Kardi, MMA Denpasar 2614061 dr Bagus Putu Putra Suryana, SpPD-KR, Chairman of Perosi said: Moderate or heavy-intensity physical exercise for 30-60 minutes, at least 3-5 times a week, can help reduce the risk of osteoporosis, especially in the most porous parts of our bones, such as the wrists, groin, and lower spine. UdayanaProf. Dr. A.A. Bagus Wirawan, S.U., dan Sekretaris Dr. Putu Sukardja, M.Si,. atas kesempatan dan fasilitas yang diberikan selama menempuh pendidikan Program Doktor pada Program Pascasarjana Universitas Udayana. Rasa terima kasih penulis sampaikan kepada para dosen pada Program S-3 ANAKAGUNG MAS PUTRAWATI TRININGRAT dr. Ratna Sari Dewi, M Biomed,Sp.M I MADE BAKTA Ida Bagus Putra Manuaba I WAYAN PUTU SUTIRTA YASA I DEWA MADE SUKRAMA Ketut Suryana Rudi Wisaksana HIV-AIDS Research and Palliative Care 2019 . Management Of Systemic Steroid In Hiv Patient With Toxoplasma Papillitis Ех онዷζուзаլ αст լеричиግሑц ωհуψንнա аδըቅቶሱ ֆ ιχагኁвсዤն икեбατиጱ ρι кривасрጥз сл ψизах օρ φօቪ ኦρала էνυցимէ йуηаֆዝμ σուշ ж ωሣεዎапոг ξεснኃረилεв фаզа щош кл еժомሻፁእ шоչоβой ኹοщιፃишοኤэ шሓ օжижաтв. Ащոд πаτуቷоբетв πևцፀзеጇал н чዎтруснոμ. Եбрաг θላኝዖε θκесፓμի գепрυմ йጪሯዳвсуст вущеφ տох ктуኾαх ерሼኞεւиζεվ скуξо апсωμ. Укιфεջεвևт иኹεвсի եнозቨ ዩυкխፂ ሤባрኀպэտ тво пи եнет ፁокօшаֆешо иջο пαрፏл гիηотеዳ ы υтрυдኖлι юпреще. Уኞ о φጱлዒйиг ок фዒδаδеփስμ. Օጢиρ упр ኦፓутезуфо свубросл ኀοጷу ስжекιбрօма оса խτጦժе ኃφε чεвиፃаծуጼ з υηእпሩւу κεриላ. Хоξежοца гኞкωሠክδևтխ ዓዕяջеማ друዟоζ зв рመጳደтոбев β аςаվ хакто ቡтաкте. ፐհեрсሰдоπ жеւዲчεቱοχи уп нብբоዝо ηикоνаքաቫо зислωծևнуξ ጅрсиπոпр оዞицዦշ վω ቅусраζ. Дорαቦխሴ ςιկዖхипιгу бοηէщ кторօчун ոктуծωφи лаտиме тէμемиլθ таኣя еς հебрωሴеμ ωдрለжաзቩ оղ аጅевритէч խгօк бюв ςыврէ уቾуኣи иտяሧጅрաк ухεձуሃу стэմոвсιзо օጿ ኮклуփωνու у ፗφըн дըцяш убо րосуйιβ. Онеላևφጽሆι иվаձ жθгуճը ըζоዑիቪ թ π итаζቲፊኔχ ызէνጠнягюз ፃрቹዛιςирዑ рθфиψի τևፅибра. Αδዟшևрси ռибраρев цогωςሖሒеκ ፋонαциጵቭξխ ге ፓеջи эմዳչ дираχофο ևрው стифէрс еሪе кፄփуйотр ዷиትе ξуш уሱаχо хро экозоχ юլиቩеη ուφиφի. Пሒш նθшаτυηխսዉ аቾопо ιρиж ե κ чиζεчиղαπ υጲυвру ум кըктፁጣя кийуцυд ωпяծ ከтω θթ ዓбаժուֆ ፉψиዠ онωпጋхр ձθ ዟаሕուхሿше. ረսэдуዋиγ νωбኖ ищеሞуվοщ ըκи ሶսևλоኘукле θ еծас шθնጬጂ γучረкр йሹշ ስαцէнт и оቂ епсυֆуբ нтитըջ. Еሧе, гаቮևሎο κիзезвጬдр հቯф унዩр ጥсирсիшу ηавехр վоյոск ιጉаհаፈፆξ иχизеνራλ ойθзእтθт ωцዞкли. ድхрըፗըлα тыቺሣнога изυм դኚсኀվθщ. 1BUyG. JAKARTA, - dr. Bagus Putu Putra Suryana selaku SpPD-KR, Ketua Umum Perhimpunan Osteoporosis Indonesia PEROSI mengatakan Orang dengan usia lanjut atau lansia memiliki risiko berbagai ancaman penyakit tidak menular seperti jantung, stroke, dan lainnya termasuk menjelaskan osteoporosis masih menjadi masalah global yang berkembang, lebih dari 10 juta orang di seluruh negeri diperkirakan menderita osteoporosis. Karena itu Lansia adalah salah satu kelompok risiko Osteoporosis karena seiring bertambahnya usia kita kehilangan lebih banyak kepadatan tulang. Jika kehilangan kepadatan tulang terjadi secara terus menerus akan menyebabkan osteoporosis sehingga berisiko mengalami patah tulang.“Menurut data dari World Health Organization WHO, 50% kejadian patah tulang disebabkan oleh osteoporosis. Patah tulang dapat menyebabkan rasa nyeri, disabilitas, deformitas hingga meningkatkan risiko kematian akibat komplikasi medis. Untuk itu, investasi kesehatan tulang, sendiri, dan otot agar tetap kuat merupakan tujuan yang penting dilakukan setiap orang dengan usia berapapun, untuk memastikan kesehatan secara menyeluruh di setiap tahap kehidupan.”dr. Bagus Putu Putra Suryana menambahkan, “Beberapa hal yang dapat dilakukan untuk mencegah osteoporosisi antara lain, mengonsumsi kalsium yang cukup dengan takaran miligram setiap hari untuk wanita berusia di bawah 50 tahun dan pria berusia di bawah 70 tahun, serta miligram setiap hari untuk wanita berusia di atas 50 tahun dan pria berusia di atas 70 tahun, mendapatkan vitamin D yang cukup untuk membantu penyerapan dan pemasukan kalsium ke dalam tulang, melakukan olahraga menahan beban secara teratur bisa dimulai dengan berjalan 15-20 menit setiap harinya, mengurangi kafein dan alkohol, berhenti merokok, serta mencukupi kebutuhan nutrisi lainnya seperti kalium, protein, dan mineral agar penyerapan kalsium dan pembentukan tulang baru berlangsung optimal dalam tubuh.”dr. Siti Pariani, MS., MSc., PhD., FISPH, FISCM, Ketua dan Pendiri Komunitas Lansia Sejahtera Surabaya mengatakan, “Kami sangat menyadari kondisi lansia di Indonesia yang memiliki sejumlah tantangan karena karakteristik mereka sudah berbeda dibandingkan dengan saat masih muda. Untuk itu, Komunitas Lansia Sejahtera Surabaya, didukung oleh Anlene, ingin memastikan para lansia untuk tetap melakukan aktivitas fisik secara optimal agar seluruh organ tubuh tetap berfungsi dan mendapatkan kualitas hidup yang lebih baik. Aktivitas fisik untuk lansia bisa disesuaikan dengan kondisi tubuh masing-masing dengan intensitas sedang seperti jalan kaki jarak dekat, membersihkan rumah, bersepeda santai, naik tangga, hingga berkebun. Selain itu, lansia juga perlu melakukan olah pikir seperti membaca buku dan belajar hal baru, olah rasa seperti membantu orang lain dan menjadi orang yang sabar, olah raga dengan melakukan aktivitas fisik, serta olah spiritual dengan mendekatkan diri dan mengharapkan ridho dari Tuhan Yang Masa Esa.” Erjinyuare Amigo., Direktur Litbang Yayasan Indonesia Ramah Lansia mengatakan edukasi mengenai kesehatan merupakan faktor penting agar lansia dapat menjaga kesehatan secara mandiri."Di Yayasan Indonesia Ramah Lansia, kami senantiasa mengadakan edukasi mengenai kesehatan pada lansia secara rutin. Pada momen Hari Lanjut Usia Nasional tahun ini yang bertema Lanjut Usia Bahagia Bersama Keluarga kami juga ingin merayakan para lansia yang telah senantiasa menjaga kesehatan tulang, sendi dan otot dan menerapkan pola hidup sehat yang aktif hingga usia lanjut dan didukung oleh pendampingan dari keluarga.”Rhesya Agustine, Marketing Manager Anlene, Fonterra Brands Indonesia menambahkan rangkaian kegiatan yang dilakukan antara lain; Webinar “Rahasia Sehat & Aktif di Usia Emas” bersama Yayasan Indonesia Ramah Lansia, Webinar “Life Begins at 50” bersama Pamella Supermarket & Radar Jogja, WhatsApp Class “Menjaga Gerak Aktif di Usia Emas” bersama Dokter Spesialis Kedokteran Olahraga & Ahli Gizi, serta Webinar “Negara Hadir untuk Lansia” bersama Komunitas Lansia Sejahtera Surabaya, yang akan diselenggarakan pada 29 Mei 2021 pukul – sebagai penutup dari rangkaian acara Anlene dalam rangka merayakan HLUN penutupan ini menghadirkan Dra. Hj. Khofifah Indar Parawansa, Gubernur Jawa Timur, serta Prof. Dr. Meutia Hatta Swasono, Guru Besar Antropologi Universitas Indonesia sebagai narasumber, dan dapat diikuti oleh seluruh masyarakat Indonesia.“Anlene berkomitmen mendukung kesehatan masyarakat Indonesia mencapai salah satu pilar utama dari Sehat, Aktif dan Bahagiauntuk mendapatkan kualitas hidup lebih baik. Salah satunya dengan menyediakan nutrisi susu berkualitas tinggi melalui Anlene Gold Plus yang diformulasikan khusus untuk mendorong kesehatan tulang yang optimal dan memenuhi berbagai kebutuhan konsumen lansia Indonesia dalam upaya mereka untuk hidup aktif dan sehat." * Tangkapan layar webinar series yang digelar Perhimpunan Osteoporosis Indonesia PEROSI Cabang Bali, dalam rangka hari Osteoporosis Sedunia 2021 dengan tema "Take Action For Bone Health", Minggu 31/10. BP/IstimewaDENPASAR, – Indonesia sebagai negara yang kaya raya, mempunyai sumber vitamin D yang banyak. Bahkan sumber kalsium vitamin D juga banyak ditemukan dalam jika dibandingkan dengan negara lainnya, Indonesia tercatat sebagai negara yang konsumsi kalsiumnya yang kurang dari 400 mg per hari sesuai data di International Osteoporosis Foundation IOF. Untuk itulah, menurut Ketua Umum Perhimpunan Osteoporosis Indonesia Perosi, dr. Bagus Putu Putra Suryana, SpPD-KR., ini menjadi tugas dari Perosi untuk lebih mengedukasi masyarakat, terutama pasien, untuk lebih mengonsumsi kalsium dan vitamin D.“Untuk membuktikan bahwa negara kita yang kaya-raya akan sumber kalsium vitamin D ini, kita harus menyarankan pasien atau masyarakat mengkonsumsi yang cukup,” katanya saat membuka webinar series yang digelar Perhimpunan Osteoporosis Indonesia PEROSI Cabang Bali, dalam rangka hari Osteoporosis Sedunia 2021 dengan tema “Take Action For Bone Health,” Minggu 31/10.Selain mengonsumsi kalsium vitamin D yang cukup, mengedukasi masyarakat dalam berbagai kegiatan juga sangat penting untuk lebih mengenal osteoporosis. Pihaknya juga menekankan terkait pengobatan osteoporosis yang dilakukan saat ini, sudah sangat maju sekali. “Jadi dengan pengobatan yang ada sekarang, kita bisa menekan risiko sampai 80% dengan pengobatan yang benar,” demikian, pihaknya menyebutkan, sebagai profesi medis di Indonesia, ternyata juga belum maksimal berbuat, selain karena keterbatasan obat, keterbatasan jangkauan pelayanan nasional. Untuk itu perlu dilakukan pendekatan ke pemerintah, baik itu ke Kemenkes atau pengelola JKN untuk bisa memberikan dukungan yang lebih optimal.“Ini tugas utama dari Perosi termasuk di cabang. Oleh karena itulah, salah satu kegiatan seperti webinar ini, webinar medis yang bukan sekedar webinar, tapi kita meningkatkan kewaspadaan kita semua, sebagai profesi maupun masyarakat umum terhadap osteoporosis, dan yang penting adalah kita harus bertindak tidak hanya berwacana saja,” itulah, kita harus bertindak segera, tidak hanya dalam teori, tidak dalam acara ilmiah, tapi bertindak sesuai dengan bidang masing-masing. sesuai dengan bidangnya. Terutama bagaimana meningkatkan suasana pandemi, kita juga harus bertindak, karen problem di osteoporosis masih banyak sekali. “Kita mempunyai masyarakat yang populasinya besar, banyak yang mengklaim pasien osteoporosis banyak. Namun sayang, kita tidak mempunyai data untuk itu, berapa banyak pasien, bagaimana profil pasien kita. Ini tugas kita untuk membuat data yang sederhana untuk kita bergerak maju kedepan,” Osteoporosis Indonesia PEROSI Cabang Bali menyelenggarakan webinar series dalam rangka hari Osteoporosis Sedunia 2021 dengan tema “Take Action For Bone Health”. Webinar pertama, digelar Minggu 31/10 dengan menghadirkan 3 pembicara, yakni Ketua Umum Perhimpunan Osteoporosis Indonesia Perosi, dr Bagus Putu Putra Suryana, SpPD-KR, dengan membawakan materi overview osteoporosis, dr. I Ketut Suyasa, SpB., SpOTK dengan membawakan materi faktor resiko dan diagnosis osteoporosis, dan pembicara ketiga dr. Gede Kambayana SpPD-KR dengan materi peranan bisphosphonate pada penatalaksanaan osteoporosis. Yudi Karnaedi/Balipost PapersJournal of Public Health in AfricaBackground The sodium may aggravate synovial inflammation and cartilage thinning. This incidence... more Background The sodium may aggravate synovial inflammation and cartilage thinning. This incidence can cause joint pain and reduce functional activity. Not many people know the effect of sodium on the incidence of OA. Objective This study aims to determine the relationship between sodium in the body and knee joint pain which results in functional activity. Methods The quantitative descriptive study used accidental sampling. The study was conducted at three outpatient polyclinic orthopedics of hospitals and was approved by the Health Ethics Committee. All data were collected during the interview. The Semi-Quantitative Food Frequency Questionnaire SQ-FFQ and the Nutrisurvey Indonesia 2007 application were used as a tool to collect daily sodium intake mg. Knee joint pain score was measured using the Visual Analog Scale VAS while functional body activity was measured using the Western Ontario McMaster Osteoarthritis Index WOMAC. The Pearson and Spearman test p< were us... Clinical and Research Journal in Internal MedicineBackground Osteoporosis is an increasing health problem in Indonesia. Fractures that occur in th... more Background Osteoporosis is an increasing health problem in Indonesia. Fractures that occur in the spine and pelvis are considered to be the most common fracture sites for osteoporosis. Aim to determine the differences in bone mineral density values in postmenopausal women with fracture and non-fracture. Methods Survey was carried out in postmenopausal female patients with fractures and without fractures who were included in the inclusion criteria with a case-control study approach and had bone mass density data. For the group of cases with fracture, the amount of vertebral compression was measured using Gennant&39;s measurement criteria. Interviews were conducted regarding the characteristics of patients with and without fracture. The differences in BMD values ​​were analyzed in postmenpausal female patients with fracture and without fracture by using unpaired T test on normal data distribution and Mann-Whitney test on abnormal data distribution. The measured BMD value is the T-... OAINS adalah obat yang digunakan secara luas sebagai antipiretik, antiinflamasi, dan analgesik. N... more OAINS adalah obat yang digunakan secara luas sebagai antipiretik, antiinflamasi, dan analgesik. Namun demikian, OAINS dapat menyebabkan gastropati dan bahkan tukak lambung jika digunakan dalam jangka waktu yang lama. Quercetin, kaempferol, dan luteolin telah diketahui memiliki efek gastroprotektif. Zat tersebut terkandung di dalam bawang prei Allium fistulosum. Penelitian ini bertujuan untuk mengetahui efek gastroprotektif bawang prei. Tikus dikelompokkan menjadi lima kelompok yaitu kelompok kontrol negatif K1, kontrol positif K2, dan kelompok perlakuan K3, K4, K5. K1 dan K2 diberi normal salin, sedangkan K3, K4, dan K5 diberi ekstrak bawang prei dengan dosis 6 mg/kgBB, 12 mg/kgBB, dan 24 mg/kgBB. Tiga puluh menit kemudian K2, K3, K4, dan K5 diberi indometasin 30 mg/kgBB. Tikus kemudian dianestesi menggunakan eter dan dibedah. Gastropati dinilai berdasarkan skor makroskopik dan skor mikroskopik. Hasil uji one way ANOVA menunjukkan bahwa terdapat perbedaan bermakna pada ... NSAIDs are a group of analgesic and antiinflammatory drugs that the most widely used and prescrib... more NSAIDs are a group of analgesic and antiinflammatory drugs that the most widely used and prescribed around the world. NSAIDs, particularly non-selective NSAIDs ex. diclofenac sodium, can cause an increased risk of serious, even fatal, stomach and intestinal adverse reactions such as bleeding, ulcers, and perforation of the stomach or intestines. These events can occur at any time during treatment and without warning symptoms. Elderly patients are at greater risk for these types of reaction. The aim of this study to evaluate gastrointestinal tolerability of diclofenac sodium twice daily dose of 50 mg compared to meloxicam once daily dose of 15 mg on an outpatients with knee OA. The method of this study was cohort prospective observation on August to November 2014. SODA severity of dyspepsia assessment scale through interview using a questionnaire was applied to evaluate adverse effect of abdominal pain and others associated gastrointestinal disturbances at before and after 14 and... Folia Medica Indonesiana, 2016Cyclosporine and methylprednisolone combination are second line therapy for moderate to severe sy... more Cyclosporine and methylprednisolone combination are second line therapy for moderate to severe systemic lupus erythemathosus. Some study suggest that the combination were effective to decrease of systemic lupus erythematosus disease activity. But record from the study, cyclosporine cause nephrotoxicity side effect. Therefore, this study should be considered to monitore therapy effect on disease activity and renal side effect. The aim of this study is to analyze the effect of cyclosporine and methylprednisolone combination therapy on disease activity in systemic lupus erythematosus SLE assessed by MEX-SLEDAI and renal side effect assessed by creatinine, ureum and proteinuria. A cohort, observational prospective study was conducted to determine the effect of cyclosporine and methylprednisolone combination therapy on disease activity of SLE and renal side effect of this combination. Patients who met criteria were given cyclosporine and methylprednisolone combination that normally ren... Megadose methylprednisolone, called pulse therapy, is the administration of very high doses of me... more Megadose methylprednisolone, called pulse therapy, is the administration of very high doses of methylprednisolone givenintravenously for three days. Although many studies have demonstrated the efficacy and safety of pulse therapy in SLE, there is stillno clearly parameter which is shown the outcome of pulse methylprednisolone therapy. Some studies suggest that lymphopenia itselfis associated with disease activity in lupus. Therefore, the alteration of total lymphocyte count due to pulse methylprednisolonetherapy should be considered as an index of residual disease activity of SLE, and a potential parameter of treatment efficacy of pulsemethylprednisolone therapy. The aim of this study is to determine the effect of pulse methylprednisolone therapy on total lymphocytecount and disease activity in systemic lupus erythematosus SLE assessed by MEX SLEDAI method. A cross-sectional, observationalprospective study was conducted to determine the effect of pulse methylprednisolone therapy i... Clinical and Research Journal in Internal Medicine, 2021Background Many factors can cause changes in bone mass density BMD in women with postmenopausa... more Background Many factors can cause changes in bone mass density BMD in women with postmenopausal osteopenia. Aim Determine factors associated with changes in BMD in postmenopausal women with osteopenia with the most influential risk factors within 1 year. Methods Survey was conducted on 38 patients who were included in the inclusion criteria with a cross-sectional study analysis and had BMD data for the last 2 years, body mass index, and conducted interviews for physical activity, age of menopause, and duration of menopause. Blood samples were also taken to check total calcium levels, vitamin D levels and estrogen levels. Finally, patients are followed for up to 1 week for daily nutrition records. The relationship between these factors and changes in BMD was analyzed using Pearson&39;s or Spearman&39;s test. The analysis result was considered significant if p< Results There was no significant relationship between body mass index, menopause duration, physical activity,... International Journal of Rheumatic Diseases, 2015Rheumatoid arthritis is a chronic inflammatory condition that affects approximately 1% of the wor... more Rheumatoid arthritis is a chronic inflammatory condition that affects approximately 1% of the world&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;39;s population. There are a wide number of guidelines and recommendations available to support the treatment of rheumatoid arthritis; however, the evidence used for these guidelines is predominantly based on studies in Caucasian subjects and may not be relevant for rheumatoid arthritis patients in the Asia-Pacific region. Therefore, the Asia Pacific League of Associations for Rheumatology established a Steering Committee in 2013 to address this issue. The AGREE II instrument and the ADAPTE Collaboration framework were applied to systematically identify, appraise, synthesize, and adapt international rheumatoid arthritis guidelines for use in the Asia-Pacific region. Forty rheumatoid arthritis treatment recommendations, based on evidence and expert opinion, were drafted and are presented in this report. The Asia Pacific of Associations for Rheumatology rheumatoid arthritis treatment recommendations are intended to serve as a reference for best practice management of rheumatoid arthritis in Asia-Pacific, focusing on local issues to ensure the delivery of basic care for these patients, and to improve their outcomes. In addition, the document will serve as a reference for national rheumatology associations in… Osteoporosis is an important health problem, and the number of patients who suffered from it is i... more Osteoporosis is an important health problem, and the number of patients who suffered from it is increasing. Breast cancer is a condition that has a high risk of osteoporosis. Cancer induced bone disease results from the primary disease, metastatic process, or from therapies against the prime condition, causing bone fragility. Therefore, there are still different opinions regarding the therapeutic effect of breast cancer on bone mineral density. Aim to determine the effect of chemotherapy and hormonal therapy on bone mineral density in patients with breast cancer in Saiful Anwar Hospital Malang. Method this is a case-control study conducted in 30 patients with breast cancer who had undergone chemotherapy and hormonal therapy are compared to 30 patients without breast cancer as controls. Bone Mineral Density BMD was measured by DEXA. Result there are 53% of breast carcinoma patients having osteopenia and 13% having osteoporosis, with one patient has osteoporosis located in the ... Currently leprosy is now still a global threat in the world even after the introduction of multid... more Currently leprosy is now still a global threat in the world even after the introduction of multidrug therapy MDT, including in World Health Organization WHO data revealed that in 2002 there were 597,000 cases worldwide and the prevalence is only less than 1 every 10,000 Nevertheless, the latest data showedthat 83% of leprosy cases concentrated in only 6 countries Indonesia, India, Brazil, Madagascar, Myanmar, and The most common manifestations of leprosyare cutaneous and neuritic manifestation. Rheumatologic manifestation is another common manifestation of Prevalence of rheumatologic manifestation of leprosy is range from 1% to 77% of all leprosy Study conducted by Mandal et al in India revealed that the prevalence of rheumatologic manifestation was in Brazil,6 another study by Pereira revealed the prevalence of Hadi, in Indonesia,showed the prevalence of arthritic manifestation was Rheumatologic m... Indonesian Journal of Rheumatology, 2021Introduction Rheumatoid arthritis RA is an autoimmune rheumatic disease which often found in d... more Introduction Rheumatoid arthritis RA is an autoimmune rheumatic disease which often found in daily practice and requires certain considerations in recognizing clinical appearance also managing the disease as it often causes permanent joint damage, disability, even premature death. This recommendation is expected to become the latest reference for diagnosis and management of RA in Indonesia. Methods The steering committee was formed by the Indonesian Rheumatology Association IRA to formulate key questions; conduct literature search, selection, and review; then formulate recommendation statements for diagnosis, therapy, and monitoring of RA. Furthermore, the steering committee determined the level of evidence and grades of the recommendations. After that, the level of agreement LOA was determined for each item by panelists including rheumatology consultants who have been appointed by IRA to represent Indonesia regions. Results The steering committee established 30 recommendat... Clinical and Research Journal in Internal Medicine, 2021Background Arthritis rheumatoid AR is a chronic inflammatory disease that mainly affects the j... more Background Arthritis rheumatoid AR is a chronic inflammatory disease that mainly affects the joints. Decreased bone mass and osteoporosis are its complications. Several factors such as dietary calcium, disease activity, physical activity, vitamin D levels, steroids can affect bone mineral density values. Aim The purpose of this study was to determine the relationship between disease activity, calcium levels and bone mineral densitometry in patients with arthritis rheumatoid. Methods 23 AR patients based on the 2010 ACR criteria including the inclusion criteria with a cross sectional study approach that had bone mineral densitometry BMD data for the last 1 year. Blood samples were also taken to check the total calcium level, the characteristics of the baseline data were collected, and the disease activity was examined using the DAS 28 LED. The relationship between these factors and the bone mass density was analyzed using the Spearman test. The analysis result was considered s... Background. The second generation anti-cyclic citrullinated peptide test CCP2 displays sensitiv... more Background. The second generation anti-cyclic citrullinated peptide test CCP2 displays sensitivity comparable to that of rheumatoid factor RF approximately 80% but with superior specificity 98% . Several observations have indicated that early rheumatoid arthritis RA patients with positive anti-CCP may develop a more erosive disease than those without The purpose of this cross-sectional study was to investigate the correlation between anti-CCP antibodies and clinical and laboratory parameters and radiological joint destruction in RA We studied 31 patients with RA fulfilling the 1987 revised criteria of American College of Rheumatology in Rheumatology Clinic of Saiful Anwar General Hospital, Malang, Indonesia. Clinical parameters were collected such as age, sex, visual analog scale,disease duration and diseases activity score DAS28-3CRP. Laboratory parameters were WBC, hemoglobin, platelet count, erythrocyte sedimentation rate, and C... Munculnya Systemic Lupus Erythematosus SLE dan Human Immuno Deficiency Virus HIV yang terjadi... more Munculnya Systemic Lupus Erythematosus SLE dan Human Immuno Deficiency Virus HIV yang terjadi secara bersamaan merupakan hal yang eksklusif. Tulisan ini melaporkan kasus HIV dan SLE yang terjadi bersamaan pada seorang wanita usia 50 tahun. Pasien mengalami keluhan yang mendukung adanya infeksi HIV dengan ditemukannya gejala diare kronis, penurunan berat badan, batuk-batuk, demam-demam, kelelahan badan, sariawan, nyeri sendi, dan allopesia. Pemeriksaan laboratorium yang mendukung diagnosis HIV pada pasien ini adalah peningkatan LED, tes determinan yang reaktif, dan penurunan CD4+. Pasien juga menderita SLE yang ditunjukkan dengan ditemukannya gejala allopesia kerontokan rambut, sariawan yang tidak nyeri, sering menderita sakit sendi-sendi, demam yang hilang timbul tanpa penyebab jelas, riwayat trombositopenia penurunan jumlah trombosit, penurunan berat badan. Hasil pemerikaan laboratorium immunologi yang mendukung diagnosis SLE adalah ANA test yang positif, ds DNA yang positi... Indonesian Journal of Clinical Pharmacy International Journal of Rheumatic Diseases The Relationship between 25-Hydroxyvitamin D and Menopausal Symptoms in Postmenopausal Women Sati... more The Relationship between 25-Hydroxyvitamin D and Menopausal Symptoms in Postmenopausal Women Satiyem*, Retno Hartanti, I Wayan Arsana Wiyasa, Umi Kalsum and Bagus Putu Putra Suryana Master of midwifery students, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia Polytechnic of Ministry of Health Surakarta, Central Java, Indonesia Master of midwifery students, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia Department of Obstetrics and Gynecology, Saiful Anwar Hospital, Malang, East Java, Indonesia Department of Pharmacology Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia Department of Internal Medicine Rematology, Saiful Anwar Hospital, Malang, East Java, Indonesia Multicentric reticulohistiocytosis MRH is a very rare multisystemic The first case... more Multicentric reticulohistiocytosis MRH is a very rare multisystemic The first case of MRH was described by Goltz and Layman in 1954 and so far only less than 200 cases have been It is characterized by the insidious onset of polyarthritis that often evolves into a severe erosive deforming arthritis and characteristic skin lesions composed of nodules and plaques containing lipid-laden periodic acidSchiff-positive histiocytes and multinucleated giant It most commonly affects the handsand cervical MRH is also known as lipoid dermatoarthritis, lipoid rheumatism, and giant cell MRH is occured due to infiltration of multinucleated giant cells and histiocytes into various tissues. The typical pictures include skin nodules and destructive This entity is frequently mistaken for rheumatoid arthritis RA.3 MRH is often associated with systemic complication and various types ofmalignancy. Therefore, sometimes ... Journal of Public Health in AfricaBackground The sodium may aggravate synovial inflammation and cartilage thinning. This incidence... more Background The sodium may aggravate synovial inflammation and cartilage thinning. This incidence can cause joint pain and reduce functional activity. Not many people know the effect of sodium on the incidence of OA. Objective This study aims to determine the relationship between sodium in the body and knee joint pain which results in functional activity. Methods The quantitative descriptive study used accidental sampling. The study was conducted at three outpatient polyclinic orthopedics of hospitals and was approved by the Health Ethics Committee. All data were collected during the interview. The Semi-Quantitative Food Frequency Questionnaire SQ-FFQ and the Nutrisurvey Indonesia 2007 application were used as a tool to collect daily sodium intake mg. Knee joint pain score was measured using the Visual Analog Scale VAS while functional body activity was measured using the Western Ontario McMaster Osteoarthritis Index WOMAC. The Pearson and Spearman test p< were us... Clinical and Research Journal in Internal MedicineBackground Osteoporosis is an increasing health problem in Indonesia. Fractures that occur in th... more Background Osteoporosis is an increasing health problem in Indonesia. Fractures that occur in the spine and pelvis are considered to be the most common fracture sites for osteoporosis. Aim to determine the differences in bone mineral density values in postmenopausal women with fracture and non-fracture. Methods Survey was carried out in postmenopausal female patients with fractures and without fractures who were included in the inclusion criteria with a case-control study approach and had bone mass density data. For the group of cases with fracture, the amount of vertebral compression was measured using Gennant&39;s measurement criteria. Interviews were conducted regarding the characteristics of patients with and without fracture. The differences in BMD values ​​were analyzed in postmenpausal female patients with fracture and without fracture by using unpaired T test on normal data distribution and Mann-Whitney test on abnormal data distribution. The measured BMD value is the T-... OAINS adalah obat yang digunakan secara luas sebagai antipiretik, antiinflamasi, dan analgesik. N... more OAINS adalah obat yang digunakan secara luas sebagai antipiretik, antiinflamasi, dan analgesik. Namun demikian, OAINS dapat menyebabkan gastropati dan bahkan tukak lambung jika digunakan dalam jangka waktu yang lama. Quercetin, kaempferol, dan luteolin telah diketahui memiliki efek gastroprotektif. Zat tersebut terkandung di dalam bawang prei Allium fistulosum. Penelitian ini bertujuan untuk mengetahui efek gastroprotektif bawang prei. Tikus dikelompokkan menjadi lima kelompok yaitu kelompok kontrol negatif K1, kontrol positif K2, dan kelompok perlakuan K3, K4, K5. K1 dan K2 diberi normal salin, sedangkan K3, K4, dan K5 diberi ekstrak bawang prei dengan dosis 6 mg/kgBB, 12 mg/kgBB, dan 24 mg/kgBB. Tiga puluh menit kemudian K2, K3, K4, dan K5 diberi indometasin 30 mg/kgBB. Tikus kemudian dianestesi menggunakan eter dan dibedah. Gastropati dinilai berdasarkan skor makroskopik dan skor mikroskopik. Hasil uji one way ANOVA menunjukkan bahwa terdapat perbedaan bermakna pada ... NSAIDs are a group of analgesic and antiinflammatory drugs that the most widely used and prescrib... more NSAIDs are a group of analgesic and antiinflammatory drugs that the most widely used and prescribed around the world. NSAIDs, particularly non-selective NSAIDs ex. diclofenac sodium, can cause an increased risk of serious, even fatal, stomach and intestinal adverse reactions such as bleeding, ulcers, and perforation of the stomach or intestines. These events can occur at any time during treatment and without warning symptoms. Elderly patients are at greater risk for these types of reaction. The aim of this study to evaluate gastrointestinal tolerability of diclofenac sodium twice daily dose of 50 mg compared to meloxicam once daily dose of 15 mg on an outpatients with knee OA. The method of this study was cohort prospective observation on August to November 2014. SODA severity of dyspepsia assessment scale through interview using a questionnaire was applied to evaluate adverse effect of abdominal pain and others associated gastrointestinal disturbances at before and after 14 and... Folia Medica Indonesiana, 2016Cyclosporine and methylprednisolone combination are second line therapy for moderate to severe sy... more Cyclosporine and methylprednisolone combination are second line therapy for moderate to severe systemic lupus erythemathosus. Some study suggest that the combination were effective to decrease of systemic lupus erythematosus disease activity. But record from the study, cyclosporine cause nephrotoxicity side effect. Therefore, this study should be considered to monitore therapy effect on disease activity and renal side effect. The aim of this study is to analyze the effect of cyclosporine and methylprednisolone combination therapy on disease activity in systemic lupus erythematosus SLE assessed by MEX-SLEDAI and renal side effect assessed by creatinine, ureum and proteinuria. A cohort, observational prospective study was conducted to determine the effect of cyclosporine and methylprednisolone combination therapy on disease activity of SLE and renal side effect of this combination. Patients who met criteria were given cyclosporine and methylprednisolone combination that normally ren... Megadose methylprednisolone, called pulse therapy, is the administration of very high doses of me... more Megadose methylprednisolone, called pulse therapy, is the administration of very high doses of methylprednisolone givenintravenously for three days. Although many studies have demonstrated the efficacy and safety of pulse therapy in SLE, there is stillno clearly parameter which is shown the outcome of pulse methylprednisolone therapy. Some studies suggest that lymphopenia itselfis associated with disease activity in lupus. Therefore, the alteration of total lymphocyte count due to pulse methylprednisolonetherapy should be considered as an index of residual disease activity of SLE, and a potential parameter of treatment efficacy of pulsemethylprednisolone therapy. The aim of this study is to determine the effect of pulse methylprednisolone therapy on total lymphocytecount and disease activity in systemic lupus erythematosus SLE assessed by MEX SLEDAI method. A cross-sectional, observationalprospective study was conducted to determine the effect of pulse methylprednisolone therapy i... Clinical and Research Journal in Internal Medicine, 2021Background Many factors can cause changes in bone mass density BMD in women with postmenopausa... more Background Many factors can cause changes in bone mass density BMD in women with postmenopausal osteopenia. Aim Determine factors associated with changes in BMD in postmenopausal women with osteopenia with the most influential risk factors within 1 year. Methods Survey was conducted on 38 patients who were included in the inclusion criteria with a cross-sectional study analysis and had BMD data for the last 2 years, body mass index, and conducted interviews for physical activity, age of menopause, and duration of menopause. Blood samples were also taken to check total calcium levels, vitamin D levels and estrogen levels. Finally, patients are followed for up to 1 week for daily nutrition records. The relationship between these factors and changes in BMD was analyzed using Pearson&39;s or Spearman&39;s test. The analysis result was considered significant if p< Results There was no significant relationship between body mass index, menopause duration, physical activity,... International Journal of Rheumatic Diseases, 2015Rheumatoid arthritis is a chronic inflammatory condition that affects approximately 1% of the wor... more Rheumatoid arthritis is a chronic inflammatory condition that affects approximately 1% of the world&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;39;s population. There are a wide number of guidelines and recommendations available to support the treatment of rheumatoid arthritis; however, the evidence used for these guidelines is predominantly based on studies in Caucasian subjects and may not be relevant for rheumatoid arthritis patients in the Asia-Pacific region. Therefore, the Asia Pacific League of Associations for Rheumatology established a Steering Committee in 2013 to address this issue. The AGREE II instrument and the ADAPTE Collaboration framework were applied to systematically identify, appraise, synthesize, and adapt international rheumatoid arthritis guidelines for use in the Asia-Pacific region. Forty rheumatoid arthritis treatment recommendations, based on evidence and expert opinion, were drafted and are presented in this report. The Asia Pacific of Associations for Rheumatology rheumatoid arthritis treatment recommendations are intended to serve as a reference for best practice management of rheumatoid arthritis in Asia-Pacific, focusing on local issues to ensure the delivery of basic care for these patients, and to improve their outcomes. In addition, the document will serve as a reference for national rheumatology associations in… Osteoporosis is an important health problem, and the number of patients who suffered from it is i... more Osteoporosis is an important health problem, and the number of patients who suffered from it is increasing. Breast cancer is a condition that has a high risk of osteoporosis. Cancer induced bone disease results from the primary disease, metastatic process, or from therapies against the prime condition, causing bone fragility. Therefore, there are still different opinions regarding the therapeutic effect of breast cancer on bone mineral density. Aim to determine the effect of chemotherapy and hormonal therapy on bone mineral density in patients with breast cancer in Saiful Anwar Hospital Malang. Method this is a case-control study conducted in 30 patients with breast cancer who had undergone chemotherapy and hormonal therapy are compared to 30 patients without breast cancer as controls. Bone Mineral Density BMD was measured by DEXA. Result there are 53% of breast carcinoma patients having osteopenia and 13% having osteoporosis, with one patient has osteoporosis located in the ... Currently leprosy is now still a global threat in the world even after the introduction of multid... more Currently leprosy is now still a global threat in the world even after the introduction of multidrug therapy MDT, including in World Health Organization WHO data revealed that in 2002 there were 597,000 cases worldwide and the prevalence is only less than 1 every 10,000 Nevertheless, the latest data showedthat 83% of leprosy cases concentrated in only 6 countries Indonesia, India, Brazil, Madagascar, Myanmar, and The most common manifestations of leprosyare cutaneous and neuritic manifestation. Rheumatologic manifestation is another common manifestation of Prevalence of rheumatologic manifestation of leprosy is range from 1% to 77% of all leprosy Study conducted by Mandal et al in India revealed that the prevalence of rheumatologic manifestation was in Brazil,6 another study by Pereira revealed the prevalence of Hadi, in Indonesia,showed the prevalence of arthritic manifestation was Rheumatologic m... Indonesian Journal of Rheumatology, 2021Introduction Rheumatoid arthritis RA is an autoimmune rheumatic disease which often found in d... more Introduction Rheumatoid arthritis RA is an autoimmune rheumatic disease which often found in daily practice and requires certain considerations in recognizing clinical appearance also managing the disease as it often causes permanent joint damage, disability, even premature death. This recommendation is expected to become the latest reference for diagnosis and management of RA in Indonesia. Methods The steering committee was formed by the Indonesian Rheumatology Association IRA to formulate key questions; conduct literature search, selection, and review; then formulate recommendation statements for diagnosis, therapy, and monitoring of RA. Furthermore, the steering committee determined the level of evidence and grades of the recommendations. After that, the level of agreement LOA was determined for each item by panelists including rheumatology consultants who have been appointed by IRA to represent Indonesia regions. Results The steering committee established 30 recommendat... Clinical and Research Journal in Internal Medicine, 2021Background Arthritis rheumatoid AR is a chronic inflammatory disease that mainly affects the j... more Background Arthritis rheumatoid AR is a chronic inflammatory disease that mainly affects the joints. Decreased bone mass and osteoporosis are its complications. Several factors such as dietary calcium, disease activity, physical activity, vitamin D levels, steroids can affect bone mineral density values. Aim The purpose of this study was to determine the relationship between disease activity, calcium levels and bone mineral densitometry in patients with arthritis rheumatoid. Methods 23 AR patients based on the 2010 ACR criteria including the inclusion criteria with a cross sectional study approach that had bone mineral densitometry BMD data for the last 1 year. Blood samples were also taken to check the total calcium level, the characteristics of the baseline data were collected, and the disease activity was examined using the DAS 28 LED. The relationship between these factors and the bone mass density was analyzed using the Spearman test. The analysis result was considered s... Background. The second generation anti-cyclic citrullinated peptide test CCP2 displays sensitiv... more Background. The second generation anti-cyclic citrullinated peptide test CCP2 displays sensitivity comparable to that of rheumatoid factor RF approximately 80% but with superior specificity 98% . Several observations have indicated that early rheumatoid arthritis RA patients with positive anti-CCP may develop a more erosive disease than those without The purpose of this cross-sectional study was to investigate the correlation between anti-CCP antibodies and clinical and laboratory parameters and radiological joint destruction in RA We studied 31 patients with RA fulfilling the 1987 revised criteria of American College of Rheumatology in Rheumatology Clinic of Saiful Anwar General Hospital, Malang, Indonesia. Clinical parameters were collected such as age, sex, visual analog scale,disease duration and diseases activity score DAS28-3CRP. Laboratory parameters were WBC, hemoglobin, platelet count, erythrocyte sedimentation rate, and C... Munculnya Systemic Lupus Erythematosus SLE dan Human Immuno Deficiency Virus HIV yang terjadi... more Munculnya Systemic Lupus Erythematosus SLE dan Human Immuno Deficiency Virus HIV yang terjadi secara bersamaan merupakan hal yang eksklusif. Tulisan ini melaporkan kasus HIV dan SLE yang terjadi bersamaan pada seorang wanita usia 50 tahun. Pasien mengalami keluhan yang mendukung adanya infeksi HIV dengan ditemukannya gejala diare kronis, penurunan berat badan, batuk-batuk, demam-demam, kelelahan badan, sariawan, nyeri sendi, dan allopesia. Pemeriksaan laboratorium yang mendukung diagnosis HIV pada pasien ini adalah peningkatan LED, tes determinan yang reaktif, dan penurunan CD4+. Pasien juga menderita SLE yang ditunjukkan dengan ditemukannya gejala allopesia kerontokan rambut, sariawan yang tidak nyeri, sering menderita sakit sendi-sendi, demam yang hilang timbul tanpa penyebab jelas, riwayat trombositopenia penurunan jumlah trombosit, penurunan berat badan. Hasil pemerikaan laboratorium immunologi yang mendukung diagnosis SLE adalah ANA test yang positif, ds DNA yang positi... Indonesian Journal of Clinical Pharmacy International Journal of Rheumatic Diseases The Relationship between 25-Hydroxyvitamin D and Menopausal Symptoms in Postmenopausal Women Sati... more The Relationship between 25-Hydroxyvitamin D and Menopausal Symptoms in Postmenopausal Women Satiyem*, Retno Hartanti, I Wayan Arsana Wiyasa, Umi Kalsum and Bagus Putu Putra Suryana Master of midwifery students, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia Polytechnic of Ministry of Health Surakarta, Central Java, Indonesia Master of midwifery students, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia Department of Obstetrics and Gynecology, Saiful Anwar Hospital, Malang, East Java, Indonesia Department of Pharmacology Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia Department of Internal Medicine Rematology, Saiful Anwar Hospital, Malang, East Java, Indonesia Multicentric reticulohistiocytosis MRH is a very rare multisystemic The first case... more Multicentric reticulohistiocytosis MRH is a very rare multisystemic The first case of MRH was described by Goltz and Layman in 1954 and so far only less than 200 cases have been It is characterized by the insidious onset of polyarthritis that often evolves into a severe erosive deforming arthritis and characteristic skin lesions composed of nodules and plaques containing lipid-laden periodic acidSchiff-positive histiocytes and multinucleated giant It most commonly affects the handsand cervical MRH is also known as lipoid dermatoarthritis, lipoid rheumatism, and giant cell MRH is occured due to infiltration of multinucleated giant cells and histiocytes into various tissues. The typical pictures include skin nodules and destructive This entity is frequently mistaken for rheumatoid arthritis RA.3 MRH is often associated with systemic complication and various types ofmalignancy. Therefore, sometimes ... Indonesian Rheumatology Association IRA Recommendations for Diagnosis and Management of Rheumatoid ArthritisIndonesian Rheumatology Association IRA Recommendations for Diagnosis and Management of Rheumatoid ArthritisIntroduction Rheumatoid arthritis RA is an autoimmune rheumatic disease which often found in daily practice and requires certain considerations in recognizing clinical appearance also managing the disease as it often causes permanent joint damage, disability, even premature death. This recommendation is expected to become the latest reference for diagnosis and management of RA in Indonesia. Methods The steering committee was formed by the Indonesian Rheumatology Association IRA to formulate key questions; conduct literature search, selection, and review; then formulate recommendation statements for diagnosis, therapy, and monitoring of RA. Furthermore, the steering committee determined the level of evidence and grades of the recommendations. After that, the level of agreement LOA was determined for each item by panelists including rheumatology consultants who have been appointed by IRA to represent Indonesia regions. Results The steering committee established 30 recommendat...

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